Body and Soul will use the 27,000 grant to create a sensory room at its new centre in Islington.
The Connection at St Martin's was awarded 50,000 for its Teen Safe project, an outreach programme that works with under-18s across London.
The charity Kids will get 50,000 for its ongoing work to develop playgrounds that can be shared by disabled and non-disabled children.
And Putney-based St Christopher's Fellowship, which runs a refuge specifically for runaway children, has been awarded 50,000 for a health worker to work at the refuge and its children's homes.
A grant of 23,000 will go to environment charity Groundwork for regeneration projects.
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