The charity, which employs 1,100 people, will focus on four core areas of support: young disabled people, refugees, young people at risk on the street, and young people in trouble with the law.
The charity, which is expecting to save around 5m a year from the restructure, says its 90 grass-roots projects in the UK will not be affected. However, the restructure will mean that some projects will be "realigned" over the next two years to fit its new core focus.
Bob Reitemeier, chief executive of the charity, said: "The jobs will be going from the infrastructure, administration and management sections of the organisation so we can focus more funds towards the needs of young people, especially those who are excluded, and influence the agenda in the Government's green paper, Every Child Matters. We will be looking at the management structure to find the best way to deliver strategy for young people first."
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