Transplantation involves taking healthy stem cells from a healthy donor's bone marrow, which is then injected into the patient's bone marrow. The new cells then take over production of blood cells
Transplant patients have to undergo high doses of chemotherapy to wipe out their own bone marrow and create space for the new cells. However, researchers at Great Ormond Street Hospital and UCL Institute of Child Health are working on a treatment that uses antibodies to clear out bone marrow. This avoids side effects of chemotherapy such as infertility, sickness and hair loss. Young patients will benefit in particular, as chemotherapy can make them too sick to tolerate a transplant
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