Dame Denise Platt told an inter-agency conference on the Children Bill that health bodies needed to look at how they would take on new child protection responsibilities outlined in the Laming report on the Victoria Climbie case.
Rachel Tyndall, chief executive of Islington Primary Care Trust, the lead trust for children's services for North and Central London, said integration was "difficult and tough" and could not happen overnight.
She said: "The NHS is different from local government and certainly very different from the voluntary and community sector."
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