The Independent Academic Research Studies (IARS) International Institute, Tomorrow's People, YMCA Birmingham and Your Own Place all received grants from NatWest's Skills & Opportunities Fund.
IARS, a think-tank focused on youth issues, said it will use the money for the delivery of a youth social entrepreneurship project. This will see an e-learning course being piloted to at least 100 young people, enabling them to become social entrepreneurs.
Dr Theo Gavrielides, founder and director of IARS said: "The unstable political, economic and social environments have hit young people the hardest.
"As we look positively into the future, this timely project supported by NatWest will challenge stale thinking while directly empowering some of the most neglected youth to pursue their entrepreneurial skills.
"It is not often that we see this trust in youth-led project ideas, and for this we are grateful to the Skills & Opportunities Fund."
Meanwhile, Tomorrow's People, which supports disadvantaged young people, who are Not in Education, Employment or Training (NEET) will use the money on its "MyMoney Tomorrow" project which aims to improve the financial capabilities and enterprise skills of disadvantaged young people in Bristol aged between 16 and 25.
"The young people we work with face many barriers to securing and sustaining jobs and further education placements," a spokesman said.
"We want to offer them the chance to develop skills and knowledge that will help them to gain the financial and social independence they need to lead more fulfilling, healthy and happy lives."
YMCA Birmingham, which provides volunteer, work and training opportunities to disadvantaged young people will use the money for its "Get Rich or Budget Tryin'" project, which aims to give young people who have faced homelessness, the skills to succeed in the workplace and to manage their own finances.
And We are Your Own Place, a Norwich-based social enterprise that provides independent living skills training to young people, the majority of whom are at risk of youth homelessness will use the money to develop its Tenancy & Independent Living Skills training project.
"The skills and confidence that participants gain through the project will enable them to keep up to date with bills, make the right decisions for them, find work that pays, keep their home and ultimately avoid future homelessness," a spokesman said.